13 Jun 2020 Ilixadencel (allogeneic inflammatory dendritic cells) is a cell-based immune primer injected intratumorally that previously has been clinically

Immunicum’s lead candidate, ilixadencel, just got a big boost in its development by being granted regenerative medicine advanced therapy designation by the FDA. The regulatory measure is designed to get promising new cell or gene therapies to market faster, and a clear signal that the FDA sees high potential in ilixadencel. BioStock reached out to […]

May 20 · FDA grants Regenerative Medicine Advanced Therapy (RMAT) designation to ilixadencel for the treatment of mRCC. The decision was made based on the results from the MERECA trial [6]. Feb 20 · In its latest corporate presentation, Immunicum reports that clinical GMP manufacturing is in place and commercial scale activities initiated. Om ilixadencel Cellterapiprodukten ilixadencel är en immunaktiverare som är lagringsbar (”off-the-shelf”) och som utvecklats för behandling av solida tumörer. Den aktiva beståndsdelen är aktiverade dendritceller som tas från friska blodgivare.

Ilixadencel

» Vid årsstämman valdes Michael Oredsson till ny styrelseordförande. Tidigare kommunicerade resultat från prekliniska studier på möss har visat att djur som behandlats med kombinationen av ilixadencel och Tidigare kommunicerade resultat från prekliniska studier på möss har visat att djur som behandlats med kombinationen av ilixadencel och Immunicum: MERECA Update Confirms Ilixadencel Benefit. Redeye Research Note. 2021-02-22. Redeye views today's update from the MERECA as a positive Immunicum's updated results from the Phase II MERECA trial with ilixadencel delivered a positive surprise. The company was selected for an ST) lämnade idag en uppdatering gällande planerade, genomförda och tidigare slutförda kliniska studier för sitt ledande program, ilixadencel. BioStock: Immunicum's ilixadencel granted regenerative medicine advanced therapy designation from FDA. Read the full interview with Sijme Anledningen tror vi huvudsakligen är ökade förväntningar om ett positivt resultat för huvudkandidaten ilixadencel i MERECA-studien, en fas Positiva topline resultat från den slutförda fas I/II studien som undersökt säkerhet och tolerans av ilixadencel hos 18 patienter med avancerad Beskrivning: Two Intuvax (ilixadencel) vaccinations (10 milj cells/vaccination) 14 days apart before nephrectomy, followed by Sunitinib treatment post-nephrectomy Immunicum meddelar lovande resultat avseende överlevnad i fas II-studien MERECA med ilixadencel i njurcancer.

Immunicum presenterade prekliniska data som stöder kombinationen av ilixadencel med cancerbehandlingar och immunterapier inklusive Immunicum AB (publ) presenterar prekliniska data för ilixadencel i kombination med cancerbehandlingar och immunterapier på årets ESMO- Immunicum lämnade uppdatering om det kliniska utvecklingsprogrammet för ilixadencel. » Vid årsstämman valdes Michael Oredsson till ny styrelseordförande.

Ilixadencel. Targeting solid tumors with an off-the-shelf, cell-based immune primer. Immunicum’s clinical program ilixadencel uses dendritic cells sourced from healthy human donors that are specifically activated to produce significant amounts of vigorous immune stimulatory factors. By administration through intratumoral injection, these cells

Immunicum’s clinical program ilixadencel uses dendritic cells sourced from healthy human donors that are specifically activated to produce significant amounts of … May 20 · FDA grants Regenerative Medicine Advanced Therapy (RMAT) designation to ilixadencel for the treatment of mRCC. The decision was made based on the results from the MERECA trial [6]. Feb 20 · In its latest corporate presentation, Immunicum reports that clinical GMP manufacturing is in place and commercial scale activities initiated. 7 maj, 2020.

Pressmeddelande 31 december 2020 Immunicum AB (publ) erhåller särläkemedelsstatus, ODD, från FDA för ilixadencel för behandling av

Uppdatering (2012-02-12): En till sak vi kan göra är att komplettera kalibreringen av modellen med informationen från Fas I/II, där ju uppföljningen sträcker sig över längre tid och inkluderar dödsfall efter mer än 48 månader . Ilixadencel is a pro-inflammatory allogeneic dendritic cell vaccine, being developed by Immunicum, for the treatment of cancer. The vaccine, called INTUVAX®, Frontline ilixadencel in combination with sunitinib as utilized in newly diagnosed patients with metastatic renal cell carcinoma in the phase 2 MERECA clinical trial has updated survival data, which indicates continued survival benefit with the combination over sunitinib alone. Se hela listan på frontiersin.org we assessed ilixadencel as a single agent and combined with sorafenib in advanced HCC. Of 17 HCC patients enrolled, 12 patients received ilixadencel at the dose of 10 × 106 cells (six as monotherapy and six in combination with sorafenib), and ﬁve received ilixadencel at the dose of 20 × 106 cells as monotherapy. GlobeNewswire - 07 dec 20 kl.

Feb. 21. News Release. Immunicum Announces Encouraging Signs of Survival Benefit in Phase II MERECA Trial of Ilixadencel in Kidney Cancer · 18. Feb. 21. 11 Feb 2019 The trial will evaluate the safety and efficacy of Immunicum's lead product in development, ilixadencel, in combination with checkpoint inhibitors 7 dec 2020 I takt med att Immunicum driver utvecklingen av ilixadencel mot nästa enarmade kliniska fas I/II-studien av ilixadencel i kombination med BioStock: Immunicums ilixadencel erhåller Renegerative Medicine Advanced Therapy från FDA. tor, maj 07, 2020 14:45 CET. Utvecklingen av Immunicums 6 Oct 2020 Cell-Based Immune Primer Ilixadencel, Alone, and Combined With Sorafenib, in Advanced Hepatocellular. Carcinoma. Front.
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Igårkom bolaget med en uppdatering från Patients in the Phase 1b part of the study will be treated with ilixadencel at an increasing dose and frequency, in combination with standard doses and schedules 29 Aug 2019 Immunicum's allogeneic dendritic cell vaccine ilixadencel has failed to better the survival rate Pfizer's Sutent achieved in a phase 2 metastatic 26 Mar 2021 relating to the designation of "Ilixadencel" as an orphan medicinal product under. Regulation (EC) No 141/2000 of the European Parliament 10 Feb 2020 The combination of ilixadencel plus sunitinib (Sutent) has evidenced favorable survival compared with sunitinib alone in patient with newly audencel (115), baltaleucel (116), cenplacel (115), eltrapuldencel (115), evagenretcel (116), ilixadencel (116), palucorcel (115), spanlecortemlocel (112.

The trial evaluated the efficacy and safety of ilixadencel combined with the targeted anticancer drug Sutent (common name: sunitinib, sunitinib; developed by Pfizer) in the first-line treatment of patients with newly diagnosed metastatic renal cell carcinoma (mRCC).
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we assessed ilixadencel as a single agent and combined with sorafenib in advanced HCC. Of 17 HCC patients enrolled, 12 patients received ilixadencel at the dose of 10 × 106 cells (six as monotherapy and six in combination with sorafenib), and ﬁve received ilixadencel at the dose of 20 × 106 cells as monotherapy.

Feb. 21. News Release. Immunicum Announces Encouraging Signs of Survival Benefit in Phase II MERECA Trial of Ilixadencel in Kidney Cancer · 18. Feb. 21.

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The mechanism of action of ilixadencel is to induce recruitment and activation of endogenous immune cells, including NK cells that subsequently promotes cross-

Immunicums ilixadencel ger nytt hopp till cancerpatienter - BioStock Immunicums ilixadencel bekämpar cancer på era fronter. Immunicum har Immunicums fas II-studie MERECA, som testar ilixadencel i patienter med njurcancer, befinner sig nu i slutfasen.